diethyl phthalate (DEP)

CAS Number
diethyl phthalate (DEP)
SIN Groups
Reason for inclusion on the SIN List
Diethyl phthalate (DEP) is an endocrine disruptor with thyroid and estrogenic activity, affecting several body functions and target organs including reproduction, liver and metabolism. The substance has been found in biomonitoring studies and in human urine. It is  categorized as an endocrine disruptor in the EU Commission Database.
Date for inclusion on the SIN List
2011 May
REACH status, appears on
Source: ECHA
CoRAP list
Registration information
Source: ECHA
Full registration, Intermediate registration
Hazard class and category code(s)
Source: ECHA
No harmonized CLP classification

Chemical information

EC number
Registered production volume
Source: ECHA
0 - 10 tonnes per annum; 1000 - 10000 tonnes per annum
(Bio)monitoring data
Yes, DEP has been found in urban lake water, in sewage treatment plant effluent water and in road run-off.
Possible uses
Source: BKH 2002; HSDB
Used in celluloid; cellulose acetate, varnishes and dopes, denaturated alcohol, fragrances and cosmetics, plastics, solid rocket propellants, polystyrene
Technical function of substances
Source: BKH 2002; HSDB
solvent, denaturing alcohol. Vehicle for fragrance and cosmetic ingredients, plasticizer, wetting agent, fixative, dispersing medium, dye carrier. 
Registered use(s) - Sector End Use (SU)
Source: ECHA
SU 10: Formulation [mixing] of preparations and/or re-packaging (excluding alloys)
SU 12: Manufacture of plastics products, including compounding and conversion
SU 13: Manufacture of other non-metallic mineral products, e.g. plasters, cement
SU 14: Manufacture of basic metals, including alloys
SU 16: Manufacture of computer, electronic and optical products, electrical equipment
SU 17: General manufacturing, e.g. machinery, equipment, vehicles, other transport equipment
SU 1: Agriculture, forestry and fishing
SU 20: Health services
SU 23: Electricity, steam, gas water supply and sewage treatment
SU 2a: Mining (without offshore industries)
SU 2b: Offshore industries
SU 4: Manufacture of food products
SU 6a: Manufacture of wood and wood products
SU 6b: Manufacture of pulp, paper and paper products
SU 8: Manufacture of  bulk, large scale chemicals (including petroleum products)
SU 9: Manufacture of fine chemicals
Registered use(s) - Chemical Product category (PC)
Source: ECHA
PC 13: Fuels
PC 14: Metal surface treatment products, including galvanic and electroplating products
PC 19: Intermediate
PC 1: Adhesives, sealants
PC 20: Products such as ph-regulators, flocculants, precipitants, neutralisation agents
PC 21: Laboratory chemicals
PC 25: Metal working fluids
PC 27: Plant protection products
PC 28: Perfumes, fragrances
PC 29: Pharmaceuticals
PC 30: Photo-chemicals
PC 31: Polishes and wax blends
PC 32: Polymer preparations and compounds
PC 34: Textile dyes, finishing and impregnating products
including bleaches and other processing aids
PC 35: Washing and cleaning products (including solvent based products)
PC 36: Water softeners
PC 37: Water treatment chemicals
PC 39: Cosmetics, personal care products
PC 3: Air care products
PC 40: Extraction agents
PC 4: Anti-freeze and de-icing products
PC 7: Base metals and alloys
PC 8: Biocidal products (e.g. disinfectants, pest control)
PC 9a: Coatings and paints, thinners, paint removes
PC 9b: Fillers, putties, plasters, modelling clay
Registered use(s) - Article category (AC)
Source: ECHA
AC 10: Rubber articles
AC 13: Plastic articles
AC 1: Vehicles
AC 2: Machinery, mechanical appliances, electrical/electronic articles
AC 31: Scented clothes
AC 32: Scented eraser
AC 34: Scented toys
AC 35: Scented paper articles
AC 36: Scented CD
AC 3: Electrical batteries and accumulators
Registered use(s) - Environmental Release Category (ERC)
Source: ECHA
ERC  7: Industrial use of substances in closed systems
ERC 10a: Wide dispersive outdoor use of long-life articles and materials with low release
ERC 11a: Wide dispersive indoor use of long-life articles and materials with low release
ERC 12a: Industrial processing of articles with abrasive techniques (low release)
ERC 1: Manufacture of substances
ERC 2: Formulation of preparations
ERC 3: Formulation in materials
ERC 4: Industrial use of processing aids in processes and products, not becoming part of articles
ERC 5: Industrial use resulting in inclusion into or onto a matrix
ERC 6a: Industrial use resulting in manufacture of another substance (use of intermediates)
ERC 6b: Industrial use of reactive processing aids
ERC 6c: Industrial use of monomers for manufacture of thermoplastics
ERC 8a: Wide dispersive indoor use of processing aids in open systems
ERC 8b: Wide dispersive indoor use of reactive substances in open systems
ERC 8c: Wide dispersive indoor use resulting in inclusion into or onto a matrix
ERC 8d: Wide dispersive outdoor use of processing aids in open systems
ERC 8e: Wide dispersive outdoor use of reactive substances in open systems
ERC 8f: Wide dispersive outdoor use resulting in inclusion into or onto a matrix
Registered use(s) - Process Category (PROC)
Source: ECHA
PROC 10: Roller application or brushing
PROC 11: Non industrial spraying
PROC 13: Treatment of articles by dipping and pouring
PROC 14: Production of preparations or articles by tabletting, compression, extrusion, pelletisation
PROC 15: Use as laboratory reagent
PROC 16: Using material as fuel sources, limited exposure to unburned product to be expected
PROC 19: Hand-mixing with intimate contact and only PPE available.
PROC 1: Use in closed process, no likelihood of exposure
PROC 21: Low energy manipulation of substances bound in materials and/or articles
PROC 24: High (mechanical) energy work-up of substances bound in materials and/or articles
PROC 2: Use in closed, continuous  process with occasional controlled exposure
PROC 3: Use in closed batch process (synthesis or formulation)
PROC 4: Use in batch and other process (synthesis) where opportunity for exposure arises
PROC 5: Mixing or blending in batch processes for formulation of preparations and articles (multistage and/or significant contact)
PROC 7: Industrial spraying
PROC 8a: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at non-dedicated facilities
PROC 8b: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities
PROC 9: Transfer of substance or preparation into small containers (dedicated filling line, including weighing)


Company Group
Company Name

3M COMPANY, 3m Center, St Paul, Ramsey, 55144-1000, MN, , USA


Berje Inc, 700 Blair Road, Carteret, Middlesex, 07008, NJ, , USA


Charkit Chemical Corporation, 32 Haviland Street, Norwalk, Fairfield, 06854, CT, , USA

Coim Group

COIM SpA, Via Manzoni 28/32,20019, Settimo Milanese (MI), Italy

COIM USA INC, 675 Billingsport Road, Paulsboro, Gloucester, 08066-1037, NJ, , USA

Eastman Chemical

EASTMAN CHEMICAL CO. B-280 OFF, 200 South Wilcox Drive, Kingsport, Sullivan, 37660-5147, TN, , USA

Global Essence

Global Essence UK Limited, Parklands Business Centre, Stortford Road, Leaden Roding, CM6 1GF, Dunmow Essex, United Kingdom


INDUSTRIAL CHEMICALS INC, 2042 Montreat Drive, Vestavia Hills, Jefferson, 35216, AL, , USA

International Flavors & Fragrances

INTERNATIONAL FLAVORS & FRAGRANCES INC, 600 Highway #36, Hazlet, Monmouth, 07730-1797, NJ, , USA


JOHN D WALSH CO INC @ RINGWOOD IND PK, 25 Executive Pkwy, Ringwood, Passaic, 07456, NJ, , USA


Koopman International B.V., Distelweg 88 1031 HH Amsterdam, , Netherlands

LIVIA group

Ostend Basic Chemicals, Stationsstraat 123 8400 Oostende, , Belgium

MAK Chemicals

MAK CHEMICALS INC, 90 Dayton Ave, Passaic, Passaic, 07055, NJ, , USA


POLYNT S.p.A., via Enrico Fermi,51, I-24020, Scanzorosciate BG, Italy

Service Provider

REACHLaw Ltd., Vänrikinkuja 3 JK 21 , FI-02600, Espoo, Finland

Sustainability Support Services (Europe) AB, Markaskälsvägen 6,22647, Lund, Sweden

Thirumalai Chemicals

Lapiz Europe Limited as Only Representative for Chemidye Manufacturing Company, No : 204-226 Talbot House Imperial Drive Rayners Lane, HA2 7HH, Harrow Middlesex, United Kingdom

Source: ECHA