tert.-Butylhydroxyanisole (BHA); tert-butyl-4-methoxyphenol

CAS Number
tert.-Butylhydroxyanisole (BHA); tert-butyl-4-methoxyphenol
SIN Groups
Reason for inclusion on the SIN List
BHA is associated with reproductive dysfunction, increased cancer risk, including breast and prostate, and a range of other chronic or irreversible health problems, often from very low levels of exposure. BHA is commonly detected in humans.
Date for inclusion on the SIN List
2011 May
REACH status, appears on
Source: ECHA
CoRAP list
Registration information
Source: ECHA
Full registration
Hazard class and category code(s)
Source: ECHA
No harmonized CLP classification

Chemical information

tert-butyl-4-methoxyphenol; Tert-bytylhydroxyanisole; Butylated hydroxyanisole; BHA; E 320
EC number
Registered production volume
Source: ECHA
100 - 1000 tonnes per annum
(Bio)monitoring data
Yes, BHA has been found in industrial wastewater.
Possible uses
Source: DHI 2006
food, food packaging, animal feed, cosmetics, rubber and petroleum products
Technical function of substances
Source: DHI 2006
stabilizers, antioxidants, preservative, scavenger of free radicals
Registered use(s) - Sector End Use (SU)
Source: ECHA
SU 11: Manufacture of rubber products
SU 8: Manufacture of  bulk, large scale chemicals (including petroleum products)
Registered use(s) - Chemical Product category (PC)
Source: ECHA
PC 27: Plant protection products
PC 29: Pharmaceuticals
PC 32: Polymer preparations and compounds
PC 39: Cosmetics, personal care products
Registered use(s) - Environmental Release Category (ERC)
Source: ECHA
ERC 2: Formulation of preparations
ERC 5: Industrial use resulting in inclusion into or onto a matrix
ERC 6d: Industrial use of  process regulators for polymerisation processes in  production of resins, rubbers, polymers
ERC 8a: Wide dispersive indoor use of processing aids in open systems
Registered use(s) - Process Category (PROC)
Source: ECHA
PROC 1: Use in closed process, no likelihood of exposure
PROC 2: Use in closed, continuous  process with occasional controlled exposure
PROC 3: Use in closed batch process (synthesis or formulation)
PROC 4: Use in batch and other process (synthesis) where opportunity for exposure arises
PROC 5: Mixing or blending in batch processes for formulation of preparations and articles (multistage and/or significant contact)
PROC 8a: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at non-dedicated facilities
PROC 8b: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities
PROC 9: Transfer of substance or preparation into small containers (dedicated filling line, including weighing)


Company Group
Company Name
Eastman Chemical

EASTMAN CHEMICAL CO. B-280 OFF, 200 South Wilcox Drive, Kingsport, Sullivan, 37660-5147, TN, US, , USA

EASTMAN CHEMICAL CO. B-280 OFF, 200 South Wilcox Drive, Kingsport, US, , USA

IMCD Group

IMCD Benelux B.V., Wilhelminaplein 32 3072 DE Rotterdam Netherlands , , Netherlands

Service Provider

Sustainability Support Services (Europe) AB, Markaskälsvägen 6 22647 Lund Sweden , , Sweden

Sustainability Support Services (Europe) AB , Markaskälsvägen 6 22647 Lund Sweden, , Sweden

Source: ECHA