Galaxolide

CAS Number
1222-05-5
Name
Galaxolide
SIN Groups
Heterocyclic compounds
Reason for inclusion on the SIN List
For Galaxolide (HHCB) endocrine effects have been reported. It is potentially persistent and bioaccumulative. It has been frequently found in humans and the environment.
Date for inclusion on the SIN List
2008 September
Registration information
Source: EURAR (2007)
Full registration
Hazard class and category code(s)
Source: ECHA
Aquatic Acute 1
Aquatic Chronic 1

Chemical information

Synonyms
HHCB; Abbalide; Chromanolide; Pearlide; 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylindeno(5,6-c)pyran; 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexa-methylcyclopenta-gamma-2-benzopyran; 6-oxa-1,1,2,3,3,8-hexamethyl-2,3,4,5,6,7,8-hexahydro-1H-benz[F]-indene; hexahydrohexamethyl cyclopentabenzopyran
EC number
214-946-9
Hazard statement code(s)
Source: ECHA
H400
H410
Registered production volume
Source: ECHA
1000 - 10000 tonnes per annum
(Bio)monitoring data
Yes, in human serum, milk, adipose tissue; In rainwater, ocean and fresh water, in suspended matter and sediment, sewage sludge, in fish, molluscs; In marine mammals and sharks.
Possible uses
Source: OSPAR 2004, Greenpeace 2005
Cosmetics, perfume industry, detergents, cleaning agents, air fresheners, fabric softeners.
Technical function of substances
Source: OSPAR 2004
Fragrance
Registered use(s) - Sector End Use (SU)
Source: ECHA
SU 11: Manufacture of rubber products
SU 12: Manufacture of plastics products, including compounding and conversion
SU 1: Agriculture, forestry and fishing
SU 20: Health services
SU 4: Manufacture of food products
SU 6b: Manufacture of pulp, paper and paper products
SU 7: Printing and reproduction of recorded media
Registered use(s) - Chemical Product category (PC)
Source: ECHA
PC 12: Fertilisers
PC 13: Fuels
PC 18: Ink and toners
PC 1: Adhesives, sealants
PC 20: Products such as ph-regulators, flocculants, precipitants, neutralisation agents
PC 21: Laboratory chemicals
PC 23: Leather tanning, dye, finishing, impregnation and care products
PC 24: Lubricants, greases, release products
PC 27: Plant protection products
PC 28: Perfumes, fragrances
PC 29: Pharmaceuticals
PC 2: Adsorbents
PC 30: Photo-chemicals
PC 31: Polishes and wax blends
PC 32: Polymer preparations and compounds
PC 34: Textile dyes, finishing and impregnating products
including bleaches and other processing aids
PC 35: Washing and cleaning products (including solvent based products)
PC 36: Water softeners
PC 37: Water treatment chemicals
PC 39: Cosmetics, personal care products
PC 3: Air care products
PC 4: Anti-freeze and de-icing products
PC 8: Biocidal products (e.g. disinfectants, pest control)
PC 9a: Coatings and paints, thinners, paint removes
PC 9b: Fillers, putties, plasters, modelling clay
Registered use(s) - Article category (AC)
Source: ECHA
AC 31: Scented clothes
AC 35: Scented paper articles
AC 36: Scented CD
Registered use(s) - Environmental Release Category (ERC)
Source: ECHA
ERC 11a: Wide dispersive indoor use of long-life articles and materials with low release
ERC 11b: Wide dispersive indoor use of long-life articles and materials with high or intended release (including abrasive processing)
ERC 1: Manufacture of substances
ERC 2: Formulation of preparations
ERC 4: Industrial use of processing aids in processes and products, not becoming part of articles
ERC 5: Industrial use resulting in inclusion into or onto a matrix
ERC 6b: Industrial use of reactive processing aids
ERC 8a: Wide dispersive indoor use of processing aids in open systems
ERC 8b: Wide dispersive indoor use of reactive substances in open systems
ERC 8c: Wide dispersive indoor use resulting in inclusion into or onto a matrix
ERC 8d: Wide dispersive outdoor use of processing aids in open systems
ERC 8f: Wide dispersive outdoor use resulting in inclusion into or onto a matrix
Registered use(s) - Process Category (PROC)
Source: ECHA
PROC 10: Roller application or brushing
PROC 11: Non industrial spraying
PROC 13: Treatment of articles by dipping and pouring
PROC 14: Production of preparations or articles by tabletting, compression, extrusion, pelletisation
PROC 15: Use as laboratory reagent
PROC 19: Hand-mixing with intimate contact and only PPE available.
PROC 1: Use in closed process, no likelihood of exposure
PROC 2: Use in closed, continuous  process with occasional controlled exposure
PROC 3: Use in closed batch process (synthesis or formulation)
PROC 4: Use in batch and other process (synthesis) where opportunity for exposure arises
PROC 5: Mixing or blending in batch processes for formulation of preparations and articles (multistage and/or significant contact)
PROC 7: Industrial spraying
PROC 8a: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at non-dedicated facilities
PROC 8b: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities
PROC 9: Transfer of substance or preparation into small containers (dedicated filling line, including weighing)
1222-05-5

Producers

Company Group
Company Name
ADAMA

ADAMA Agriculture BV, Arnhemseweg 87, Postbus 354, 3829 AK Leusden, Netherlands

AlEn

ALEN USA, 14825 Northwest Fwy, Houston, Harris, 77040, TX, , USA

BERJE

Berje Inc, 700 Blair Road, Carteret, Middlesex, 07008, NJ, , USA

FIRMENICH

Firmenich Inc, 250 Plainsboro Rd, Plainsboro, Middlesex, 08543, NJ, , USA

Givaudan

Givaudan UK OR1, Kennington Road, TN24 0LT, Ashford, United Kingdom

International Flavors & Fragrances

INTERNATIONAL FLAVORS & FRAGRANCES INC, 600 Highway #36, Hazlet, Monmouth, 07730-1797, NJ, , USA

International Flavours & Fragrances I.F.F. (Great Britain) Ltd., Duddery Hill, CB9 8LG, Haverhill Suffolk, United Kingdom

JOHN D WALSH

JOHN D WALSH CO INC @ RINGWOOD IND PK, 25 Executive Pkwy, Ringwood, Passaic, 07456, NJ, , USA

SC JOHNSON & SON

SC JOHNSON & SON INC WAXDALE FACILITY, 8311 16th St, Sturtevant, Racine, 53177, WI, , USA

Service Provider

Chemical Inspection & Regulation Service Limited, Singleton House, Laurence Street, Co. Louth, Drogheda, Ireland

NetSun EU B.V., Blaak 40, Fifth floor, 3011 TA, Rotterdam, Netherlands

Sustainability Support Services (Europe) AB, Markaskälsvägen 6,22647, Lund, Sweden

Symrise

SYMRISE INC, 1636 Bushy Park Road, Goose Creek, Berkely, 29445-6338, SC, , USA

Source: ECHA