2,4,6-tribromophenol

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CAS Number
118-79-6
Name
2,4,6-tribromophenol
SIN Groups
(Poly)halogenated aromatics
Reason for inclusion on the SIN List
This substance has endocrine disrupting properties. In vitro studies have shown binding to a thyroid hormone transport protein. Animal studies have shown the substance to alter the rate of development and increase abnormalities. In addition it interferes with the synthesis of oestrogen and thyroid hormones.
Date for inclusion on the SIN List
2014 October
REACH status, appears on 
Source: ECHA
CoRAP list
Registration information 
Source: ECHA
Full registration
Hazard class and category code(s) 
Source: ECHA
No harmonized CLP classification
» Similar substances in SINimilarity

Chemical information

Synonyms
tribromophenol
EC number
204-278-6
Registered production volume 
Source: ECHA
0 - 10 tonnes per annum
(Bio)monitoring data 
TriBP was detected in human serum and breast milk in a general population from Okinawa in Japan. TriBP was also detected in high concentrations in serum from cats diagnosed with feline hyperthyroidism. (Norrgran et al., 2012; Fujii et al., 2014a; Fujii et al., 2014b)
Possible uses 
Source:
This substance has endocrine disrupting properties. In vitro studies have shown binding to a thyroid hormone transport protein. Animal studies have shown the substance to alter the rate of development and increase abnormalities. In addition it interferes with the synthesis of estrogen and thyroid hormones.
Technical function of substances 
Source: 
Antiseptic, wood preservative, flame retardant intermediate. Source: HSDB
Registered use(s) - Sector End Use (SU) 
Source: ECHA
SU 12: Manufacture of plastics products, including compounding and conversion
Registered use(s) - Chemical Product category (PC) 
Source: ECHA
PC 32: Polymer preparations and compounds
Registered use(s) - Environmental Release Category (ERC) 
Source: ECHA
ERC 4: Industrial use of processing aids in processes and products, not becoming part of articles
Registered use(s) - Process Category (PROC) 
Source: ECHA
PROC 14: Production of preparations or articles by tabletting, compression, extrusion, pelletisation
118-79-6

Producers

Company Group
Company Name
Albemarle Corporation

ALBEMARLE CORP SOUTH PLANT, 2270 Highway 79 South, Magnolia, Columbia County, 71753-9129, AR, US, , USA

ALBEMARLE CORP SOUTH PLANT, 2270 Highway 79 South, Magnolia, Columbia, 71753-9129, AR, US, , USA

Chemtura

GREAT LAKES CHEMICAL - SOUTH PLANT, 324 Southfield Cutoff, El Dorado, Union, 71730, AR, US, , USA

Service Provider

TÜV SÜD Industrie Service GmbH, IS-USR-MUC Westendstraße 199 80686 Munich Germany , , Germany

TÜV SÜD Industrie Service GmbH, IS-USR-MUC Westendstraße 199 80686 Munich Germany, , Germany

TÜV SÜD Industrie Service GmbH, S-USR-MUC Westendstraße 199 80686 Munich Germany, , Germany

TÜV SÜD Industrie Service GmbH, Westendstraße 199 80686 München Germany , , Germany 

Source: ECHA