CAS Number
SIN Groups
Highly reactive compounds
Reason for inclusion on the SIN List
Classified CMR according to Annex VI of Regulation 1272/2008
Date for inclusion on the SIN List
2008 September
Registration information
Source: ECHA
Full registration, Intermediate registration
Hazard class and category code(s)
Source: ECHA
Flam. Liq. 3
Carc. 1B
Acute Tox. 3 *
Acute Tox. 3 *
Acute Tox. 3 *
Skin Corr. 1B
Skin Sens. 1

Chemical information

1-Chlor-2,3-epoxypropan; epichlorhydrin;1-cloro-2,3-epoxipropano; 1-chloro-2,3-époxypropane
EC number
Hazard statement code(s)
Source: ECHA
Registered production volume
Source: ECHA
100000 - 1000000 tonnes per annum; 10 - 100 tonnes per annum
Possible uses
Source: US EPA
explosives, fuels, epoxy resins used in coatings, adhesives, and plastics, synthetic glycerine, textiles, paper, inks and dyes, solvents, surfactants, and pharmaceuticals
Technical function of substances
Source: US EPA
binder, stabilizer
Registered use(s) - Sector End Use (SU)
Source: ECHA
SU 10: Formulation [mixing] of preparations and/or re-packaging (excluding alloys)
SU 11: Manufacture of rubber products
SU 12: Manufacture of plastics products, including compounding and conversion
SU 20: Health services
SU 24: Scientific research and development
SU 8: Manufacture of  bulk, large scale chemicals (including petroleum products)
SU 9: Manufacture of fine chemicals
Registered use(s) - Chemical Product category (PC)
Source: ECHA
PC 19: Intermediate
PC 21: Laboratory chemicals
PC 35: Washing and cleaning products (including solvent based products)
PC 39: Cosmetics, personal care products
Registered use(s) - Environmental Release Category (ERC)
Source: ECHA
ERC 1: Manufacture of substances
ERC 2: Formulation of preparations
ERC 4: Industrial use of processing aids in processes and products, not becoming part of articles
ERC 6a: Industrial use resulting in manufacture of another substance (use of intermediates)
ERC 6c: Industrial use of monomers for manufacture of thermoplastics
ERC 6d: Industrial use of  process regulators for polymerisation processes in  production of resins, rubbers, polymers
ERC 8a: Wide dispersive indoor use of processing aids in open systems
ERC 8d: Wide dispersive outdoor use of processing aids in open systems
Registered use(s) - Process Category (PROC)
Source: ECHA
PROC 13: Treatment of articles by dipping and pouring
PROC 14: Production of preparations or articles by tabletting, compression, extrusion, pelletisation
PROC 15: Use as laboratory reagent
PROC 19: Hand-mixing with intimate contact and only PPE available.
PROC 1: Use in closed process, no likelihood of exposure
PROC 21: Low energy manipulation of substances bound in materials and/or articles
PROC 2: Use in closed, continuous  process with occasional controlled exposure
PROC 3: Use in closed batch process (synthesis or formulation)
PROC 4: Use in batch and other process (synthesis) where opportunity for exposure arises
PROC 5: Mixing or blending in batch processes for formulation of preparations and articles (multistage and/or significant contact)
PROC 6: Calendering operations
PROC 8a: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at non-dedicated facilities
PROC 8b: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities
PROC 9: Transfer of substance or preparation into small containers (dedicated filling line, including weighing)


Company Group
Company Name

3M Belgium BVBA/SPRL, Hermeslaan 7 1831 Diegem, , Belgium

AGC Group

ADVANCED BIOCHEMICAL EUROPE SPRL, rue de Ransbeek 310 1120 Brussels, , Belgium

AGC Chemicals Europe Ltd., York House Hillhouse, FY5 4QD, Thornton Cleveleys Lancashire, United Kingdom

Air Products & Chemicals

Air Products (Chemicals) PLC, Hersham Place Technology Park Molesey Road, KT12 4RZ, Walton on Thames Surrey, United Kingdom

Akzo Nobel

Akzo Nobel Industrial Paints, S. L., Poligono Industrial Can Prunera Apartado 9,8760, Vallirana, Spain


Archroma Distribution and Management Germany GmbH, Kasteler Str. 45,65202, Wiesbaden, Germany

Archroma France, SAS, Rue du Flottage,60354, Trosly-Breuil, France

Archroma Germany GmbH, Kasteler Str. 45,65201, Wiesbaden, Germany

Archroma Ibérica S.L.U., ZAL-Prat c/Cal Coracero, 46-56,8827, El Prat de Llobregat, Spain

Archroma Italy S.r.l., Via Manzoni 37,20030, Palazzolo Milanese, Italy

Archroma UK Ltd, Bowling Old Lane, BD5 7JL, Bradford, United Kingdom


Ashland Chemical Hispania SL (0341), Partida Povet,37, ES-12578, Benicarlo Castillon de la Plana, Spain


BASF Espanola S.L., Calle Can Ràbia, n. 3-5,8017, Barcelona, Spain

BASF Health and Care Products France S.A.S., 49, Avenue Georges Pompidou,92593, Levallois-Perret Cedex, France

BASF Italia S.p.A., Via Marconato 8,20811, Cesano Maderno, Italy

BASF Oy, Tammasaarenkatu 3,180, Helsinki, Finland

BASF Personal Care and Nutrition GmbH, Henkelstr. 67 40589 Düsseldorf, , Germany

BASF SE, Carl-Bosch-Str. 38,67056, Ludwigshafen am Rhein Rheinland-Pfalz, Germany


ZACHEM S.A., Wojska Polskiego 65, 85-825, Bydgoszcz, Poland


Caplinq Europe BV, Agro Business Park 75 6706PV Wagningen, , Netherlands

Cardolite Corperation

Cardolite Specialty Chemicals Europe NV, Wijmenstraat 21 K bus 2, B-9030, Mariakerke (Gent), Belgium


CCD (Germany) GmbH, Graf-Adolf-Strasse 68,40210, Düsseldorf, Germany


Clariant Ibérica Producción S.A., Avda. Baix Llobregat, 3-5,8970, Sant Joan Despí Barcelona, Spain

Clariant Produkte (Deutschland) GmbH, Am Unisys-Park 1,65843, Sulzbach am Taunus, Germany

Cytec Industries

Cytec Engineered Materials Ltd. OR, Abenbury Way Wrexham Industrial Estate, LL13 9UZ, Wrexham, United Kingdom


Dow Belgium B.V.B.A., Havenlaan 7 B 3980 Tessenderlo, , Belgium

DOW BENELUX B.V. - OR2, Postbus 48, 4530 AA, Terneuzen, Netherlands

DOW DEUTSCHLAND ANLAGENGESELLSCHAFT mbH, Am Kronberger Hang 4, D-65824, Schwalbach, Germany

The Dow Chemical Company - Freeport, 2310 N Brasoport Blvd, Freeport, Brazoria, 77541, TX, , USA


DYNACHEM INC, 1 Maple Grove Road Po Box 19, Georgetown, Vermillion, 61846-0019, IL, , USA


EMERALD PERFORMANCE MATERIAL, 2020 Front Street Ste 100, Cuyahoga Falls, Summit, 44223, OH, , USA


Envigo Consulting Limited, Woolley Road Alconbury PE28 4HS Huntingdon Cambridgeshire, , United Kingdom

Ferro Corporation

Ferro Spain S.A., Carretera Valencia - Barcelona Km 61.5,12550, Almazora (Castellon), Spain

General Electric

GE Water & Process Technologies BVBA, Toekomstlaan 54,2200, Herentals, Belgium

GE Water & Process Technologies France SAS, Immeuble NEPTUNE II 35 bis Avenue Saint-Germain des Noyers,77400, SAINT-THIBAULT-DES-VIGNES, France

GEO Specialty Chemicals

GEO SPECIALTY CHEMICALS UK LIMITED, Charleston Road Hardley, Hythe,, SO45 3ZG, Southampton Hampshire, United Kingdom


Harke Services GmbH-OR3, Xantener Str.1,45479, Mülheim an der Ruhr, Germany


Henkel AG & Co. KGaA, Henkelstrasse 67,40191, Duesseldorf North-Rhine Westfalia, Germany

Henkel Electronic Materials (Belgium) N.V., Nijverheidsstraat 7,2260, Westerlo, Belgium

Henkel Global Supply Chain B.V., Brugwal 11, 3432NZ, Nieuwegein, Netherlands

Henkel Ireland Operations and Research Limited, Tallaght Business Park Whitestown,24, Dublin, Ireland

Henkel Ltd., Apollo Court, 2 Bishop Square Business Park, AL10 9EY, Hatfield, United Kingdom

Henkel Nederland B.V., Brugwal 11, 3432 NZ, Nieuwegein, Netherlands


Hexion B.V., Seattleweg 17, building 4, 3195 ND, Pernis-Rotterdam, Netherlands

Hexion B.V. OR, Seattleweg 17, building 4, 3195 ND, Pernis-Rotterdam, Netherlands

Hitachi Chemical

Hitachi Chemical Europe GmbH, Berliner Allee 22,40212, Duesseldorf Germany, Germany

Huntsman International

Huntsman Advanced Materials (Europe) BVBA, Everslaan 45, B-3078, Everberg, Belgium

Huntsman Advanced Materials (Europe) BVBA OR-C, Everslaan 45, B-3078, Everberg, Belgium

Huntsman Advanced Materials (Europe) BVBA OR-U, Everslaan 45, B-3078, Everberg, Belgium

ICC Industries

ICC CHEMICAL CORPORATION, 460 Park Avenue, New York, New York, 10022-1906, NY, , USA

ICC Industries B.V., Hoogoorddreef 9, Afrikagebouw NL-1101 Amsterdam, , Netherlands

ICL Industrial Products

ICL Europe Coöperatief U.A. (OR1), Koningin Wilhelminaplein 30 Prinsenhof 1062 KR Amsterdam, , Netherlands

Illinois Tool Works

ITW Engineered Polymers, A Division of ITW Ireland, Bay 150 Shannon Industrial Estate, na, Shannon Co.Clare, Ireland


Innospec Limited (OR1), Innospec Manufacturing Park Oil Sites Road, CH65 4EY, Ellesmere Port Cheshire, United Kingdom

Jiangsu Yangnong Chemical Group

JIANGSU YANGNONG CHEMICAL GROUP CO., LTD.(KONSENS OR), Graf-Adolf-Str. 70,40210, Duesseldorf, Germany


Kemira Oyj, Porkkalankatu 3 P.O.Box 330, FI-00101, HELSINKI, Finland


Isola GmbH, Isolastr,52353, Dueren NRW, Germany


LORD Germany GMBH, Ottostrasse 28,41836, Hueckelhoven North Rhine - Westphalia, Germany


CADENCE CHEMICAL CORPORATION, 945 Long Ridge Rd, Stamford, Fairfield, 06902, CT, , USA

NAMA Chemicals

NAMA Germany, Teichstrasse 38, D-79539, Lörrach, Germany

Nedastra Holding

Blue Cube Germany Assets GmbH & Co. KG, Buetzflether Sand 2,21683, Stade, Germany

Blue Cube Netherlands B.V. – OR1, Herbert H. Dowweg 5 (P.O. Box 48, 4530 AA Terneuzen, the Netherlands), 4542 NM, Hoek, Netherlands

Olin Corporation

OLIN BLUE CUBE, FREEPORT, TX, 2301 N. Brazosport Blvd., Freeport, Brazoria, 77541, TX, , USA


Panasonic Industrial Devices Materials Europe GmbH, Ennshafenstrasse 30,4470, Enns, Austria

PPG Industries

PPG Central (UK) Ltd - OR3, Needham Rd, IP14 2AD, Stowmarket Suffolk, United Kingdom


SABIC Innovative Plastics BV, Plasticslaan 1, 4612 PX, Bergen op Zoom Netherlands, Netherlands

SCAS Group Laboratories

SCAS Europe S.A./N.V., Leonardo Da Vincilaan 19, B-1831, Diegem, Belgium

Service Provider

Cambridge Environmental Assessments part of ADAS UK Ltd, ADAS Boxworth Battlegate Road, Boxworth, CB23 4NN, Cambridge Cambridge, United Kingdom

Chemical Inspection & Regulation Service Limited, Singleton House, Laurence Street, Co. Louth, Drogheda, Ireland

Dr. Knoell Consult - OR - B8, Dynamostr. 19 68165, Mannheim, Germany

Experien Chemical Services (Europe) Limited, PO Box 170, YO7 9AN, Thirsk, United Kingdom

INFO_CARE_USP, Tiberiusweg 9, 3453 KZ, De Meern, Netherlands


ITS Testing Services (UK) Ltd 12, Caleb Brett House 734 London Road, RM20 3NL, West Thurrock, Grays Essex, United Kingdom

KIST Europe Forschungsgesellschaft mbH_14, Campus E 71, Saarbruecken 66123, Germany

REACH24H CONSULTING GROUP, Suite 1E, Paramount Court, Corrig Road, Sandyford, Dublin 18, Dublin, Ireland

REACHLaw Ltd., Vänrikinkuja 3 JK 21 , FI-02600, Espoo, Finland

Stewardship Chemicals 27, Green Lowe Farm, Shawclough Road Waterfoot, BB4 9SA, Rossendale Lancashire, United Kingdom

TÜV SÜD Iberia S.A.U. (052), C/ Frederic Mompou 4A, 1º 4º,8960, Sant Just Desvern (BCN) Barcelona, Spain

TÜV SÜD Industrie Service GmbH, IS-USR-MUC Westendstraße 199 80686 Munich, , Germany

Showa Denko

Showa Denko Europe GmbH OR1, Konrad-Zuse-Platz 4, D-81829, Munich, Germany


Sigma-Aldrich Logistik GmbH, Riedstrasse 2,89555, Steinheim, Germany

SNF Group

SNF S.A.S., ZAC de Milieux,42163, Andrézieux, France

SNF Holding Company

POLYCHEMIE INC., 3080 Port And Harbor Drive, Pearlington, Hancock, 39520, MS, , USA


Solenis Netherlands B.V., Fascinatio Boulevard 522 2909 VA CAPELLE A/D IJSSEL, , Netherlands


INOVYN Deutschland GmbH, Hans-Boeckler-Allee,20,30173, Hannover, Germany

INOVYN France S.A.S., RUE DE CLICHY 25,75009, PARIS, France

RHODIA OPERATIONS, 40 rue de la Haie Coq,93306, AUBERVILLIERS, France

SOLVAY CHEMICALS INC, 3737 Buffalo Speedway, Houston, Harris, 77098, TX, , USA

Spolchemie Group

CHS Epi, a.s., Revolu?ní 1930/6,40032, Ústí nad Labem, Czech Republic


Sterling Pharma Solutions Ltd, Dudley NE23 7QG Cramlington Northumberland, , United Kingdom

The Carlyle Group

Axalta Coating Systems Germany GmbH & Co. KG, Christbusch 25,42285, Wuppertal, Germany

Tricon Energy Group

TRICON INTERNATIONAL, LTD, 777 Post Oak Blvd, Suite 550, Houston, Harris, 77056, TX, , USA


UNIVAR USA INC MARLBOROUGH, 221 Boston Post Road, East, Marlborough, Middlesex, 01752-3545, MA, , USA

Zeon Chemicals

Zeon Chemicals L.P., 4100 Bells Lane, Louisville, Jefferson, 40211, KY, , USA

Source: ECHA