4,4'-methylenedianiline, MDA

CAS Number
4,4'-methylenedianiline, MDA
SIN Groups
Aromatic amines
Reason for inclusion on the SIN List
Classified CMR according to Annex VI of Regulation 1272/2008
Date for inclusion on the SIN List
2008 September
REACH status, appears on
Source: ECHA
Candidate list
Authorisation list (annex XIV)
Registration information
Source: ECHA
Full registration
Hazard class and category code(s)
Source: ECHA
Carc. 1B
Muta. 2
Skin Sens. 1
Aquatic Chronic 2

Chemical information

4,4'-Methylendianilin; 4,4'-metilendianilina; 4,4'-methylenedianiline; Diaminodiphenyl methane; DDM
EC number
Hazard statement code(s)
Source: ECHA
H370 **
H373 **
Registered production volume
Source: ECHA
10000 - 100000 tonnes per annum
Registered use(s) - Sector End Use (SU)
Source: ECHA
SU 8: Manufacture of  bulk, large scale chemicals (including petroleum products)
SU 9: Manufacture of fine chemicals
Registered use(s) - Chemical Product category (PC)
Source: ECHA
PC 19: Intermediate
PC 24: Lubricants, greases, release products
PC 32: Polymer preparations and compounds
Registered use(s) - Environmental Release Category (ERC)
Source: ECHA
ERC  7: Industrial use of substances in closed systems
ERC 1: Manufacture of substances
ERC 6a: Industrial use resulting in manufacture of another substance (use of intermediates)
ERC 6c: Industrial use of monomers for manufacture of thermoplastics
Registered use(s) - Process Category (PROC)
Source: ECHA
PROC 15: Use as laboratory reagent
PROC 1: Use in closed process, no likelihood of exposure
PROC 2: Use in closed, continuous  process with occasional controlled exposure
PROC 3: Use in closed batch process (synthesis or formulation)
PROC 8b: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities
PROC 9: Transfer of substance or preparation into small containers (dedicated filling line, including weighing)


Company Group
Company Name
Air Products & Chemicals

AIR PROD & CHEM HAMILTON BLVD FAC, 7201 Hamilton Boulevard, Allentown, Lehigh, 18195-9642, PA, , USA


ELANTAS Europe S.R.L., Via Antolini n.1,43044, Collecchio, frazione Lemignano (PR) Emilia-Romagna, Italy

ELANTAS PDG INC, 5200 N. Second St., Saint Louis, Saint Louis City, 63147-3122, MO, , USA

Ausimont Industries

SOLVAY SPECIALTY POLYMERS USA, LLC, 4500 Mcginnis Ferry Rd, Alpharetta, Forsyth, 30005, GA, , USA


BASF Antwerpen N.V., Haven 725, Scheldelaan 600,2040, Antwerpen 4 Antwerpen, Belgium

BASF CORPORATION, 8404 River Rd, Geismar, Ascension, 70734, LA, , USA

Bayer AG

Covestro Deutschland AG, Kaiser-Wilhelm-Allee 60 51373 Leverkusen, , Germany


Carl Bechem GmbH, Weststraße 120,58089, Hagen, Germany


Clariant Plastics & Coatings (Deutschland) GmbH, Brüningstrasse 50 65929 Frankfurt am Main, , Germany

Evonik Industries

Evonik Nutrition & Care GmbH, Rellinghauser Straße 1 - 11,45128, Essen, Germany

Evonik Technochemie GmbH, Gutenbergstraße 2,69221, Dossenheim Baden-Württemberg, Germany


Henkel Global Supply Chain B.V., Brugwal 11, 3432NZ, Nieuwegein, Netherlands

Henkel Nederland B.V., Brugwal 11, 3432 NZ, Nieuwegein, Netherlands

Hitachi Chemical

Hitachi Chemical Europe GmbH, Berliner Allee 22,40212, Duesseldorf Germany, Germany

Huntsman International

HUNTSMAN CORPORATION - THE WOODLANDS CORPORATE SITE, 10003 Woodloch Forest Dr., The Woodlands, Montgomery, 77380, TX, , USA


Royce International, 3400 S. Tamiami Trail, Suite 300, Sarasota, Sarasota, 34239, FL, , USA


Solvay Specialty Polymers Italy S.p.A., Viale Lombardia 20,20021, BOLLATE, Italy

Wanhua Group

BorsodChem Zrt. - OR, Bolyai ter 1., H-3700, Kazincbarcika, Hungary

Source: ECHA