CAS Number
SIN Groups
Aromatic amines
Reason for inclusion on the SIN List
Classified CMR according to Annex VI of Regulation 1272/2008
Date for inclusion on the SIN List
2008 September
REACH status, appears on
Source: ECHA
Candidate list
Authorisation list (annex XIV)
Registration information
Source: ECHA
Full registration
Hazard class and category code(s)
Source: ECHA
Carc. 1B
Acute Tox. 4 *
Aquatic Acute 1
Aquatic Chronic 1

Chemical information

4,4'-Methylenbis[2-chloranilin]; 4,4'-metilenbis[2-cloroanilina]; 4,4'-méthylènebis[2-chloroaniline]
EC number
Hazard statement code(s)
Source: ECHA
Registered production volume
Source: ECHA
1000 - 10000 tonnes per annum
Possible uses
Source: ATSDR; Inchem; US EPA; US NTP
epoxy resins, urethane foam, gaskets, sport, boots, roller skate wheels, shoe soles, rolls and belt drives in cameras, computers and copy machines, wheels and pulleys, for escalators and elevators, home appliances, glues, plastics, and adhesives, Rubbers, roofing and wood sealing, liquid polyurethane elastomers, shoe soles; rolls for postage stamp,
Technical function of substances
Source: ATSDR; Inchem; US EPA; US NTP
curing agent, coating
Registered use(s) - Sector End Use (SU)
Source: ECHA
SU 10: Formulation [mixing] of preparations and/or re-packaging (excluding alloys)
SU 11: Manufacture of rubber products
SU 12: Manufacture of plastics products, including compounding and conversion
SU 16: Manufacture of computer, electronic and optical products, electrical equipment
SU 17: General manufacturing, e.g. machinery, equipment, vehicles, other transport equipment
SU 18: Manufacture of furniture
SU 8: Manufacture of  bulk, large scale chemicals (including petroleum products)
Registered use(s) - Chemical Product category (PC)
Source: ECHA
PC 14: Metal surface treatment products, including galvanic and electroplating products
PC 19: Intermediate
PC 32: Polymer preparations and compounds
Registered use(s) - Article category (AC)
Source: ECHA
AC 10: Rubber articles
AC 13: Plastic articles
AC 1: Vehicles
AC 2: Machinery, mechanical appliances, electrical/electronic articles
Registered use(s) - Environmental Release Category (ERC)
Source: ECHA
ERC 10a: Wide dispersive outdoor use of long-life articles and materials with low release
ERC 11a: Wide dispersive indoor use of long-life articles and materials with low release
ERC 2: Formulation of preparations
ERC 5: Industrial use resulting in inclusion into or onto a matrix
ERC 6c: Industrial use of monomers for manufacture of thermoplastics
ERC 6d: Industrial use of  process regulators for polymerisation processes in  production of resins, rubbers, polymers
Registered use(s) - Process Category (PROC)
Source: ECHA
PROC 15: Use as laboratory reagent
PROC 1: Use in closed process, no likelihood of exposure
PROC 21: Low energy manipulation of substances bound in materials and/or articles
PROC 24: High (mechanical) energy work-up of substances bound in materials and/or articles
PROC 3: Use in closed batch process (synthesis or formulation)
PROC 4: Use in batch and other process (synthesis) where opportunity for exposure arises
PROC 5: Mixing or blending in batch processes for formulation of preparations and articles (multistage and/or significant contact)
PROC 6: Calendering operations
PROC 8b: Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities
PROC 9: Transfer of substance or preparation into small containers (dedicated filling line, including weighing)


Company Group
Company Name

ANDERSON DEVELOPMENT COMPANY, 1415 E Michigan St, Adrian, Lenawee, 49221, MI, , USA


CHEMTURA CORPORATION, 199 Benson Road, Middlebury, New Haven, 06762-3218, CT, , USA

Chemtura Sales Europe B.V. (NL10), Ankerweg 18 1041AT Amsterdam, , Netherlands

Coim Group

COIM USA INC, 675 Billingsport Road, Paulsboro, Gloucester, 08066-1037, NJ, , USA


THE DOW CHEMICAL COMPANY, 2020 Dow Center, Midland, Midland, 48674, MI, , USA


K-I Chemical Europe S.A./N.V., Avenue Louise 326, Box3,1050, Brussels, Belgium

LUC Group

Limburgse Urethane Castings NV, Slakweidestraat 18, B-3630, Maasmechelen, Belgium

Rit-Chem Co.

RIT-CHEM CO., INC., 1 Zeiss Dr, Thornwood, Westchester, 10594, NY, , USA


Royce International, 3400 S. Tamiami Trail, Suite 300, Sarasota, Sarasota, 34239, FL, , USA

Service Provider

Chemical Inspection & Regulation Service Limited, Singleton House, Laurence Street, Co. Louth, Drogheda, Ireland

REACHLaw Ltd, Vänrikinkuja 3 JK 21 , FI-02600, Espoo, Finland

Source: ECHA